NZ_CM000441.1 RefSeq region 1 4094363 + ID=NZ_CM000441.1:1..4094363;Dbxref=taxon:455631;Is_circular=true;Name=ANONYMOUS;country=Canada: Quebec;gb-synonym=Clostridium difficile QCD-66c26;gbkey=Src;genome=chromosome;isolate=QCD-66c26;isolation-source=patient with severe CDAD;mol_type=genomic DNA;nat-host=Homo sapiens;note=binary toxin positive%3B tcdC delta-117 and 18bp deletion;old-name=Clostridium difficile QCD-66c26 NZ_CM000441.1 antiSMASHv7.0.0beta1-67b538a9 protocluster 1405309 1447498 + aStool=rule-based-clusters;category=NRPS;contig_edge=False;core_location=[1425308:1427498];cutoff=20000;detection_rule=cds(Condensation and (AMP-binding or A-OX));neighbourhood=20000;product=NRPS;protocluster_number=2;tool=antismash NZ_CM000441.1 antiSMASHv7.0.0beta1-67b538a9 proto_core 1425309 1427498 + aStool=rule-based-clusters;tool=antismash;cutoff=20000;detection_rule=cds(Condensation and (AMP-binding or A-OX));neighbourhood=20000;product=NRPS;protocluster_number=2 NZ_CM000441.1 antiSMASHv7.0.0beta1-67b538a9 antismash_cand_cluster 1405309 1447498 + SMILES;candidate_cluster_number=2;contig_edge=False;detection_rules=cds(Condensation and (AMP-binding or A-OX));kind=single;product=NRPS;protoclusters=2;tool=antismash NZ_CM000441.1 antiSMASHv7.0.0beta1-67b538a9 antismash_region 1405309 1447498 + candidate_cluster_numbers=2;contig_edge=False;product=NRPS;region_number=2;rules=cds(Condensation and (AMP-binding or A-OX));tool=antismash NZ_CM000441.1 antiSMASHv7.0.0beta1-67b538a9 CDS 1405477 1406268 + locus_tag=ctg1_1260;transl_table=11;translation=LYKVDLNSDLGESFGTYKIGLDEEVLKYISSANIACGFHAGDPSHMEKTVQLAKKNGVKIGAHPGFLDLIGFGRREMKITKQEAKDYTKYQLGALMAFASSNGCNIQHVKPHGALYNMAAKDKELAMGICEAIYEVDKDIILLGLYNSEMINSAKEIGLRFANEVFADRAYDNNGFLVPRSVEGAVIHDTKHAIDRVVRMVKEGTVETLTGEVIHIKADSICVHGDNPKAIEFVKEIRKRFELEGIEVCPLENIEVCSSENIV NZ_CM000441.1 antiSMASHv7.0.0beta1-67b538a9 CDS 1406297 1407517 + locus_tag=ctg1_1261;transl_table=11;translation=MSTKNITDKTKNKKDVGALIGAAFIMATSAIGPGFLTQTAQFTQDFGPNFSFVILITTILFIGAQVNVWRVIGVSGLRGQDIANKIIPGLGYLVAFLVALGGLAFNIGNVGGAALGMNVMFNMNMTLGTVLSGLIAIFVFMSKNSNSLVDKITKFLALGMIIIVGYVAISNHPPVGEAVSRMVKPENPKGLIFPIITLLGGSVGGYITFAGGHRLIDGGITGEENIKEITKSSLLGILVDTMMRVLLFLAILAVVSKGLQLDPENPAASAFKFSAGAIGYKFFGLVLWSAAITSVIGAAYTSVSFLKTLNPFIDKYEKYFIIAFIAISTLIMAFIGKPATLLILAGALNGLILPITLGIMLIASKRKDIVGDYKHPTWLLIFGLIVVLISAYTGITSLSSLGALFA NZ_CM000441.1 antiSMASHv7.0.0beta1-67b538a9 CDS 1407537 1408232 + locus_tag=ctg1_1262;transl_table=11;translation=METRYLISGDKAVVAEFGNEISEDINKKVISFMRAIEISNLKGIVTEMVPTYRSLMISYNPLEIDFDSLIENLKKIEDNLESIVLPKPKIHEIPVCYDEVFGIDIKNVASYNNLTVDEVIKIHTSREYLIYMLGFTPGFPYLGGMDERIATPRLEVPRTKIYGGSVGIAGSQTGVYPIDSPGGWQIIGRTPLKLYDENREEQILLRAGDFIKFVPITLDEFIEIEKNNLSI NZ_CM000441.1 antiSMASHv7.0.0beta1-67b538a9 CDS 1408262 1409248 + locus_tag=ctg1_1263;transl_table=11;translation=MGFKVELGGFQTLIQDRGRVGYGQYGVSGCGAMDEYAHRVGNILVGNSEDEASLEVLMLGPTITFDEYTQIAVTGGDLGAKINGKEIQNWRSYQINPGDVLSFRGVKSGARAYVSIAGGIDVPLAMGSKSTYTRSKIGGFEGRALKKGDYINTFIQEKDFTINKKLNSKYIPTYSSEIVLRIVKGPQFDAFSNGEVEKFLSNKYKVTNEIDRMGCRLDGESIKHLNGADIISDGISYGAIQVPGHGKPIIMLSDRQTSGGYTKIGNVISVDLYKLAQAKPNDVVKFELVDIYEAHRLLREQEDKIQDIYKSMKNIRVVKAKVLNDIAV NZ_CM000441.1 antiSMASHv7.0.0beta1-67b538a9 CDS 1409467 1410033 - gene_functions=biosynthetic-additional (rule-based-clusters) MannoseP_isomer,other (smcogs) SMCOG1148:hypothetical protein (Score: 117.8%3B E-value: 1e-35);gene_kind=biosynthetic-additional;locus_tag=ctg1_1264;sec_met_domain=MannoseP_isomer (E-value: 8.3e-06%2C bitscore: 23.5%2C seeds: 129%2C tool: rule-based-clusters);transl_table=11;translation=MLGEKMRNIRKSKKKTLSDVSKLTDLSISYISQIERDAIEPSLSSLRKIAEVLDTPLYMFMDDNNTDDLVIRKEDRVMMKFPKSEMFYEIVSPMPTTEFTPSILFVEFELKPESEDAKDYIYHASEEIMVVTSGVVDICMGEKVVRLNPGDSTFIKANVPHKIINPSKDTIARGYGVISPPIWPIKSK NZ_CM000441.1 antiSMASHv7.0.0beta1-67b538a9 CDS 1410385 1411452 + gene_functions=biosynthetic-additional (smcogs) SMCOG1268:mandelate racemase/muconate lactonizing enzyme (Score: 363%3B E-value: 2.3e-110);gene_kind=biosynthetic-additional;locus_tag=ctg1_1265;transl_table=11;translation=MKITDIKFEKLRIKLKKPVVVSFGVIEYGESVILKIETDEGYCGFGEAAPLAAVTGEVLDNVLSVLLMFKKELIGKDPLDIETIHTIMDGIIIGNTSAKAAIDIALYDIKGKIMNAPLYKVLGGFDSKVQTDITISIDKPEKMAVEALERVKEGFRILKLKAGINPEDDIEAVKLIREAVGESIRIRIDANQGWNVNSSINTIKKLEEFNVDAIEQALPHWDLDGTAYIRNKSNTKIMIDESLHSPIDAIKAIKKNAVDTFNIKLMKSSGIYPAIKINNIAEASGVNCMLGCMLETRIGITAAANLIASKKNITEADLDSFMFCEESKDISGGFVMDGDIMNLVNKPGLGIEVNL NZ_CM000441.1 antiSMASHv7.0.0beta1-67b538a9 CDS 1411471 1412631 + locus_tag=ctg1_1266;transl_table=11;translation=MNTLFSNPGSILAVMTSMIALGFYLQRYKAIKSLGPALTIIIMGIILSNLKVVPVSTELYGTISTYAIPVSMTIMLMSVDLKEMTKLSREPLIAIFVAVLTVSIMAFLFGLVFAEKISEGWKVAGMFVGTYTGGSANLTAIGTGLNVSRQTLAAANAADYVIGVPTLIFMFALPAILKNSKKFKKLWPYHVEETELEDCQNEEFMESKEWSIKDIAWMLAIGFVVTEVSTILAGYFNSSFSSAARILLVTTISIIIAQLKPVKKLKGNLDLGLFVALFFLCTIGFSVDIKEFLGSTFTITLYCFSIIFASFVFHLGITRLLKIKYQYVILSIVGAIADGPTSALVAASAKWNSLVSVAVVMGVIGGVLGNYAGISVAYAIKMSLGL NZ_CM000441.1 antiSMASHv7.0.0beta1-67b538a9 CDS 1412644 1414740 + locus_tag=ctg1_1267;transl_table=11;translation=LIKFKLYISGLYSGNVIFDGDLLIEKLNPFTNKIESLKPISKEENTYYLNLTKIDLKSLFNNFDVYTKSLVNTDKDTVINNLGETHSKLNEYIWVQRNKKFPLDIIIVDNKIVGFICLSRETCTILIMDGYEEYTVLKEWEKTHKNEEIYSIRFGGNYMIDMKDGIKLSTDVYLPDFVDSTKKAPTILMRTPYGKENDKEIYYKYVQRGYAVVIQDVRGRNESEGKWEPMIHEREDGDSTINWIVSQEWSSGIVGMLGASYLGYVQWAAASSGNKHLKALVSIVTSGSPFIDIPRKGGAFVSGMLAWAFMVSRNKVDRSKMVRDDWDDVLNIRPIENIPVEALGYRIEFLEEWLKRVEKDEYWDLMDWHLQKDKINVPALVVSGWYDDNSMGTTEALDVIKDYEKGKRKAILGPWMHNSNTLRDINGISLGNSSLRYDLDYNYLLWFDKYLKGIENNIDTTAPVEYYSVGFNKWKTEENWPIINKIDKSMYLISDGNANTSLGNGRLVFDNDLEEKYDSYIYNPKDPSVQLIDMSENEVGVPNNYKDLEKRSDMLCYTSDAFSEEFTVTGDIKLEFFASSSAKDTDWVIKIMDVDLDGNSIKLADGILSARFRNSFYKSEFMEEGEIYKFTIITSKISNTFKVGHKIRLDITSSAKNFIFQNSNTKEGYNSIEYIEAKNTIYHGGKYPSKLILPIENK NZ_CM000441.1 antiSMASHv7.0.0beta1-67b538a9 CDS 1414899 1415243 - locus_tag=ctg1_1268;transl_table=11;translation=MEIKRYEGTGRMSRAVVHNNTVYLCGQTHAEGGVIEQTTEVLAKIEDLLNKYGSDKQHLLSVTIYLRDMKDFEAMNSVWDAWVEKGFEPARACVEARLAREHLLVEMSVVAATK NZ_CM000441.1 antiSMASHv7.0.0beta1-67b538a9 CDS 1415535 1416425 + gene_functions=transport (smcogs) SMCOG1166:transporter%2C EamA family (Score: 65.9%3B E-value: 6.7e-20);gene_kind=transport;locus_tag=ctg1_1269;transl_table=11;translation=MSSTIKSNRIKGIMFIIASALGFAMMSAFVKLAGDLPSFQKVFFRNLVSAIIAFWLIIKHKGSLTGKKENLKVLLYRSIFGTLGVIFNYYAIDKLMLSDANMLNKMSPFLVVIFCAIALKEKINVKQIGAIIIAFIGALFIIKPTFSVEVIPYLGGIAGAVFAAMAYTCLRVLGDREDYYTIVFFFSVFSLVTVGPIAFAVYEPMTLMQLIYLLLGGVFASLGQFGITLAYKYAPAKEISIFDYSNIIFSAILSIFLFNVYPDMLSVVGYLIVFSAAFYMFLYNKKLDKLDKEKKK NZ_CM000441.1 antiSMASHv7.0.0beta1-67b538a9 CDS 1416643 1417929 + gene_functions=biosynthetic-additional (smcogs) SMCOG1079:oxidoreductase (Score: 128.2%3B E-value: 7.6e-39);gene_kind=biosynthetic-additional;locus_tag=ctg1_1270;transl_table=11;translation=MEKVKVAVIGAGNRGTYAYAPYIYENSDICEIVAVAEPKKGRRELFTQKYNLDSKNVFETLEDFFKHDKMADAVIIATNDDRHYDVAKLALEKGYHVLLEKPMSNSLDGLVHIDDLCDKYKDKIFMICHVLRYSPFYNKLKEIVESKKLGELVSIQYNENIGYWHFAHSFTRGNWRNSNETSPLILAKSCHDMDILLYLVGSRCKKISAFGSLKHLNNQNASGEMAQNCLQCLVEKKCPYSAKRIYLEKDRSINRAVHINPTEENLLNILKTSPYGRCVYRCDNNVVDNMVNILQFENGVTATFNLCAFTKENGRTIKLMFSHGEVGGDLNKNEIRIKKFGKNEEIVMNPSNQQNMVEEYDRNLIAEFIKLVSNKELEKGRVAAKEAIQSHVMAFAAEYSRVSDEVVYIEEFFDSAKQMTKEIEETIF NZ_CM000441.1 antiSMASHv7.0.0beta1-67b538a9 CDS 1418139 1418417 + locus_tag=ctg1_1271;transl_table=11;translation=MFIARKVSIKSIINSQSLYIEYGNLFTYLNISKIVVHRKSIGVVIQKYIKKKINTAPRDLYSNPKNDKKPIPITVKIQKVIPKKQQKIKIQK NZ_CM000441.1 antiSMASHv7.0.0beta1-67b538a9 CDS 1418692 1419279 - locus_tag=ctg1_1272;transl_table=11;translation=MKLYLSADIEGTCGIVNWDETKLECEFSQHYRTQMSKEITAACDGATQSGVHEILVKDAHDSGRNINPNILPENVKILRGWTKDPLVMMAGIDESFDACIFTGYHSGATCNGNPLSHTMDIDYDYFKINDEIASEFTINAYIAAYYNVPVAFLSGDEMLCESAKKLNPNIVTVPVSKGIGNGSISIHPNLALKKN NZ_CM000441.1 antiSMASHv7.0.0beta1-67b538a9 CDS 1419845 1420321 - locus_tag=ctg1_1273;transl_table=11;translation=MKEILINPIGKICIQGEEVFIKLDKKYVPALNELDDFSHLNVFWWADGFDNPELRSILETPKPYKSGPNVIGIFATRSPIRPNPIALTAVQIINIDHENGIIKIPYIDANDNSPVIDLKPYTPSVDRVENPSVPKWCSHWPKSVEKSGEFNWEDEIEF NZ_CM000441.1 antiSMASHv7.0.0beta1-67b538a9 CDS 1420422 1421591 - gene_functions=biosynthetic-additional (smcogs) SMCOG1244:amidohydrolase (Score: 447%3B E-value: 7.8e-136);gene_kind=biosynthetic-additional;locus_tag=ctg1_1274;transl_table=11;translation=MLNIRTLCHEINDWIINIRRDLHKTPELGLEEFQTKKKIIKYLNEIGINYIEYKNHTGITAYINVSPNFETVAIRADIDALPITEELNYSYKSINIGKMHACGHDAHTAILLGTCNILFKLKNYLNVNVKFFFQPAEETIGGAQLMIEDGCLENPNVKYIFGLHVNPNINKNLIELKYNTLNASTDTLQLTVHGSKCHGAYPHQGIDAIVISAHIITALQTIVSRNTNPTDSVVISLGKIEGGIKENIVCDKVVIRGTLRTLTPETREFSKKRIREICDFTCKTFGGSISVEIEEGYPALINSNHLVDYVKQNAVELFGEENIILKDSPTLGAEDFSYFLRHCEGAFYHLGCANREKNITSPLHTSTFDIDEDCLITGVMLHVKNVLSF NZ_CM000441.1 antiSMASHv7.0.0beta1-67b538a9 CDS 1421754 1422617 + locus_tag=ctg1_1275;transl_table=11;translation=MLGIIAPSGPLRNTSLEEIKFNLESYGYEVKFSESCSLNYKGYLAGNDDIRARDIEDMFLDKDVDIIMCLRGGYGTTRILDKINYDIIKQNPKPFIGFSDITGLNLAFYKNCGLLPYHGIMAANVGKWDKFTYKSLVNALEFKDDLYLENPKEEKIYTVCEGKAEGIIMGGNLSLIIATMGTKYEIDAKDKILFIEEIGEPQYKLDRMLTQLYSSGKLEECNGIIFGDFKDCIEENDLMELLIEFANKVNKPSIYNLQSGHCIPMITIPLGRMCELDATEKIVKLKK NZ_CM000441.1 antiSMASHv7.0.0beta1-67b538a9 CDS 1422688 1423281 + locus_tag=ctg1_1276;transl_table=11;translation=MSDDRIIDFNELKNKVKDSDVDKFEQYIYNLYFSVMDGKMSMAEFSRKIFDYMRDNNISQEKFMKIQKQFMERYGMDTEEVEKQLRNFGIDPSTAGFMSNNTSSKVSTEDLESFKKSAGFYEKYGEKIQPKSCITTFIKNDLNDINVIIDQEKIMLCSDRKINLMDSELNEFLLEYKNMFNKKIKVVMCETTNKYDY NZ_CM000441.1 antiSMASHv7.0.0beta1-67b538a9 CDS 1423532 1424167 - locus_tag=ctg1_1277;transl_table=11;translation=MDNLLNELEALKSNLDNLPIEKIENYDLSKTALFIIDVNNGFARQGALYSPRVESLIKPIEMFTKKISNKLNRVIAFTDSHTPKSIELLSYPVHCLENDVESELVDELKSIENLQILPKNSTNGFFALENLDFDNIDNIIIVGDCTDICIYQFAITLKSYFNQHNIEKNIVVPMNLVDTYDIPNIHPAEILNLVFFNSMIQNGVNVLKEIR NZ_CM000441.1 antiSMASHv7.0.0beta1-67b538a9 CDS 1424247 1424978 - locus_tag=ctg1_1278;transl_table=11;translation=MNIYAHRGFSGKYPENTILAFKKCLYMDIYGIELDVHRTKDGKIVVIHDEKVDRTFNGHGFVKDFTLRKLKTLNSSFEGYQNNKECKIPTLEEVLILISPTDLILNIELKTDKINYPNIEKDVLELILKYNMKNRVLISSFNSNSLKNFHKLDPSVKTGLLCYLPINNVVNFAKFLGNSYLHPPLVLVNESLIELCHKNLLGVNVYTVNEEDDILHCLKLNVDGIFTNYPDIASNLLHSKQYS NZ_CM000441.1 antiSMASHv7.0.0beta1-67b538a9 CDS 1425309 1427498 + NRPS_PKS=Domain: AMP-binding (249-635). E-value: 1e-90. Score: 296.1. Matches aSDomain: nrpspksdomains_ctg1_1279_AMP-binding.1;gene_functions=biosynthetic (rule-based-clusters) NRPS: AMP-binding,biosynthetic (rule-based-clusters) NRPS: Condensation,biosynthetic-additional (smcogs) SMCOG1002:AMP-dependent synthetase and ligase (Score: 284.8%3B E-value: 1.7e-86);gene_kind=biosynthetic;locus_tag=ctg1_1279;sec_met_domain=Condensation (E-value: 4.4e-05%2C bitscore: 20.4%2C seeds: 272%2C tool: rule-based-clusters),AMP-binding (E-value: 3.1e-94%2C bitscore: 313.6%2C seeds: 417%2C tool: rule-based-clusters);transl_table=11;translation=MYEVNLERAMNYWMDLLDDYTNIAKIPNDFFYKDCSDEVVDEVFKMNIEKHERLIQYSKVNNISIDSIIETIYGLILQKYIYEDDVVFGKTMNIIPIRVRVRQSEKFIDVVRKLKRQWSRSLEYGYYLLSDIENKNHLNTKLINTIFIAKSFDLSYDYDIEKKGYDLSVIVYTKRALKIKIKYKPSIYKRETIRRILNQFDYIIEQIIEDNDILIEDLEFVCKEEEKVLLEDFNNNQYEVPYDKSYVDLFREQVKVTPSNIAARDENRKLTYKELDEVTDKLAGYLNHIGVESEDIVAVMLPRDINIIITAIGIMKSGGAFFPIDTSNPEERLNYLLEDSNAKVVITTDELKSKVVNENTIVLDINDEEMFKLGYELTEKITSSNCAYTISTSGSTGRPKTIAIEHKSLVNMCYYSVKSISATENDICGIYLSFSFDAVMKQLFPYLLVGASIDIMPEEAKFDEYTVNEYCEENDITILALPTAFARLFIQNCNNNSLRVVQTGGERLKGYRKRNYELYNEYGPTEFTVVSTSFHVDREYGKIPIGKPIFNTYAYVLDKKNKLCPIGAPGELCLSGIQISRGYLNKKGLTEQVFVENPYKTCEYNKLMYRTGDLVRWLDDGNLDYIGRMDNQVKIDEFRIELYEIENIINNITEIKSVVCISRTNDDGDMYICAYYVIDEEDSGKINERTIREYLNEHLPPYMIPTIIMRIDKIPVTPIGKVNKKALPE NZ_CM000441.1 antiSMASHv7.0.0beta1-67b538a9 aSDomain 1426056 1427213 296.1 + aSDomain=AMP-binding;aSTool=nrps_pks_domains;database=nrpspksdomains.hmm;detection=hmmscan;domain_id=nrpspksdomains_ctg1_1279_AMP-binding.1;evalue=1.00E-90;label=ctg1_1279_AMP-binding.1;locus_tag=ctg1_1279;protein_end=635;protein_start=249;specificity=substrate consensus: X;tool=antismash;translation=FREQVKVTPSNIAARDENRKLTYKELDEVTDKLAGYLNHIGVESEDIVAVMLPRDINIIITAIGIMKSGGAFFPIDTSNPEERLNYLLEDSNAKVVITTDELKSKVVNENTIVLDINDEEMFKLGYELTEKITSSNCAYTISTSGSTGRPKTIAIEHKSLVNMCYYSVKSISATENDICGIYLSFSFDAVMKQLFPYLLVGASIDIMPEEAKFDEYTVNEYCEENDITILALPTAFARLFIQNCNNNSLRVVQTGGERLKGYRKRNYELYNEYGPTEFTVVSTSFHVDREYGKIPIGKPIFNTYAYVLDKKNKLCPIGAPGELCLSGIQISRGYLNKKGLTEQVFVENPYKTCEYNKLMYRTGDLVRWLDDGNLDYIGRMDNQVKI NZ_CM000441.1 antiSMASHv7.0.0beta1-67b538a9 CDS_motif 1426245 1426283 11.6 + aSTool=nrps_pks_domains;database=abmotifs;detection=hmmscan;domain_id=nrpspksmotif_ctg1_1279_0001;evalue=2.20E-03;label=NRPS-A_a2;locus_tag=ctg1_1279;protein_end=325;protein_start=312;tool=antismash;translation=GIMKSGGAFFPID NZ_CM000441.1 antiSMASHv7.0.0beta1-67b538a9 CDS_motif 1426467 1426526 22.3 + aSTool=nrps_pks_domains;database=abmotifs;detection=hmmscan;domain_id=nrpspksmotif_ctg1_1279_0002;evalue=4.50E-07;label=NRPS-A_a3;locus_tag=ctg1_1279;protein_end=406;protein_start=386;tool=antismash;translation=AYTISTSGSTGRPKTIAIEH NZ_CM000441.1 antiSMASHv7.0.0beta1-67b538a9 CDS_motif 1427001 1427090 38.8 + aSTool=nrps_pks_domains;database=abmotifs;detection=hmmscan;domain_id=nrpspksmotif_ctg1_1279_0003;evalue=2.90E-12;label=NRPS-A_a6;locus_tag=ctg1_1279;protein_end=594;protein_start=564;tool=antismash;translation=PIGAPGELCLSGIQISRGYLNKKGLTEQVF NZ_CM000441.1 antiSMASHv7.0.0beta1-67b538a9 CDS_motif 1427181 1427246 29.9 + aSTool=nrps_pks_domains;database=abmotifs;detection=hmmscan;domain_id=nrpspksmotif_ctg1_1279_0004;evalue=1.60E-09;label=NRPS-A_a8;locus_tag=ctg1_1279;protein_end=646;protein_start=624;tool=antismash;translation=YIGRMDNQVKIDEFRIELYEIE NZ_CM000441.1 antiSMASHv7.0.0beta1-67b538a9 CDS 1427909 1429837 + locus_tag=ctg1_1280;transl_table=11;translation=MNKKLPKGAYGEVSGKDYVPYITDKSRTGGNVAVLIIGIILAAIFAASTTYSGMKAGLTVAAGIPGAIIGSAFVGAFARSKGILGKNLIQGMSSGGESVASGFIFVLPAVILIGSQITFFEGLAVGVGGVLFGIGIAAIVHNYLIVEEHGKLMYPESMAISETLVASEAGGDSIKYMGIGFVISGFITVLTGSFLNVANNVMSLVGSKFYKWKFDIEVNPLLLGIGFIVGLEVSLTMFAGSILSNFGIAPLIGYFTDMAKDGAMVWNNPAMPLNQMDVGAISSSYVKYIGAGMMLCGGIIGAIKLIPTIIASIKETLKAKSSAGEGEEGSSIQMILLLGGVVIGFLAAFLISGNIVMAIIGAIISLLLSLLFVIVAGRLTGTIGTSNLPVSGMTIASLVIVTLVFVIMGWTDLEANKSLLLFGSFIVVAIAIAGGYTQSQKVTYIIGGSKNEMQRYFTIASIVGVIVVVGVILLLSDQLRATGDNVQFALPQANLMSTLTSGIMSGSLPWVMIIVGVFMAIVLYALNLPIMTIAIGFYLPIATTSIILVGALIRLFVELVSKTEKEKEVKVSNGISLSSGLVAGGSIIGLIGIILQVTGVVTPKVPSGFAATNSMAIALLVVLVVLTTLPIVLSKVKNNEQE NZ_CM000441.1 antiSMASHv7.0.0beta1-67b538a9 CDS 1429824 1430171 + gene_functions=biosynthetic-additional (rule-based-clusters) PF05402;gene_kind=biosynthetic-additional;locus_tag=ctg1_1281;sec_met_domain=PF05402 (E-value: 1.8e-09%2C bitscore: 35.5%2C seeds: 60%2C tool: rule-based-clusters);transl_table=11;translation=MSKSNDVLDIVFKITDGLEYEVAENSVVTILEKQDHKIQKFFRKLKARIPKYKKIELDEYSSFVFLQIDGQRTVREIGKNLEAKYGEESHPLYERLLVFLNHIEVNCHYIERLDI NZ_CM000441.1 antiSMASHv7.0.0beta1-67b538a9 CDS 1430413 1432401 - gene_functions=transport (smcogs) SMCOG1000:ABC transporter ATP-binding protein (Score: 120.2%3B E-value: 1.9e-36);gene_kind=transport;locus_tag=ctg1_1282;transl_table=11;translation=VAIGKTQIINILKNNRLEIKVNYMNLMTLENISKSYSEKKLLENISLGINEGEKIGLIGVNGTGKSTLLKIIAGVEESETGNITKTNGIRIEYLPQNPTYNENSTVLEQVFNGTSEELKLLGEYQEILEKLNSNFTEELNKKLLSVHEKIDALNLWDLESEAKSVLTKLGINDFNQKIAELSGGQRKRVSLASALITPCEFLILDEPTNHLDNDTIDWLEEYLNSRKGSLLMITHDRYFLDRVTNRIIELDKGRLFSYDGNYSIFLEKKMERLSLEASIEDKRQNLIRTELAWVKRGAQARSTKQKARLQRFDELMNRDSFKPDENLDISVASSRLGNKIIEIHNISKSFEENTVIDNLEYTLTRTDRIGIIGKNGMGKSTLINILNGEIEPDSGYISIGETVKIGCFSQDDSHMNIDMRAIDYVKEASDYIETSDGTRITASQMCERFLFNGTMQYTLIGKLSGGERRRLHLLKILMTAPNVLLLDEPTNDLDIETLKILEEYLDEFKGVVVTVSHDRYFLDRICNKIFAYEGNGKIHIYTGNYSDYLIYREIQGIEFEESKRESVKKDDSTTLKKEKPKNDKKLKFSYNEQREFENIDSDIEKLESKIATLDESTAKFSTDFTKLQEILDEKSKLEKELEYKYERWEYLNNLADEIANNK NZ_CM000441.1 antiSMASHv7.0.0beta1-67b538a9 CDS 1432358 1433140 - locus_tag=ctg1_1283;transl_table=11;translation=MSKKSKRRKINKLKLTIVITVLFLALLSIYEILFSNPNKKGNIKSQETMQNKNNTTDDSKNNQSSTKKQEDNNIKPTFSYSSIPDNIKNKMIGKSMPTDEPISFDSLSYLKLTYYGFDEKTHQGEMIVNSELAPEVVDIFKELYEKKYPIEKIKLIDDYDAVDEKSMSDNNTSSFCYRTIAGTNVVSNHGKGRAIDINPLQNPQVSGNDVTPKISTVYADRSSTKFGMIKKGDDCYNAFVSRGWSWGGYWKNPDYQHFEK NZ_CM000441.1 antiSMASHv7.0.0beta1-67b538a9 CDS 1433223 1434671 - NRPS_PKS=Domain: Aminotran_1_2 (135-468). E-value: 1.1e-25. Score: 82.4. Matches aSDomain: nrpspksdomains_ctg1_1284_Aminotran_1_2.1;gene_functions=biosynthetic-additional (rule-based-clusters) Aminotran_1_2,biosynthetic-additional (smcogs) SMCOG1019:aminotransferase (Score: 335.6%3B E-value: 6.6e-102);gene_kind=biosynthetic-additional;locus_tag=ctg1_1284;sec_met_domain=Aminotran_1_2 (E-value: 5.7e-24%2C bitscore: 82.7%2C seeds: 357%2C tool: rule-based-clusters);transl_table=11;translation=LIFSNLKLNDNEPIYIQLKNYISDMISKGLIPDNSKLPSTRELSQLLQVSRNSVVLTYEELKSEGLIYSISGKGTFVKSKNKSSNTTWSLNWDCLENTYSKKANELDIIKSEIPWSSDLISFKSISPDGDLFDMEELKKSFLNRISLEGHKLLNYGYAQGYKPLIDYLLEYMTNKGADISNKDILITNGFTEGFDIIMSSFTQEKDYIICENPTHNTAIKIMKSHNLNILGVDINEDGLDFNMLEDNLVKYKNKIKFAYITPSYHNPTGIVMTPENRYKFYNLMKKYNIAIIEDGFNEELLYNSSHIFPICSLDNMNNGVVYIGSFSKILFPGMRIGWIFADKKVINKLESVKRCRNIHVSFLDQGILFDYLSNGGFEKYIKKIRKFYGDKFNFAYKCIKKYIKTEYILGDGGLHIFIKLKNIDTRVLLEKCYEKNVIFMPGDLFFTDNSGFDTLRLGFSRLSFEDIEIGIKIIGETINEMF NZ_CM000441.1 antiSMASHv7.0.0beta1-67b538a9 aSDomain 1433268 1434266 82.4 - aSDomain=Aminotran_1_2;aSTool=nrps_pks_domains;database=nrpspksdomains.hmm;detection=hmmscan;domain_id=nrpspksdomains_ctg1_1284_Aminotran_1_2.1;evalue=1.10E-25;label=ctg1_1284_Aminotran_1_2.1;locus_tag=ctg1_1284;protein_end=468;protein_start=135;tool=antismash;translation=ELKKSFLNRISLEGHKLLNYGYAQGYKPLIDYLLEYMTNKGADISNKDILITNGFTEGFDIIMSSFTQEKDYIICENPTHNTAIKIMKSHNLNILGVDINEDGLDFNMLEDNLVKYKNKIKFAYITPSYHNPTGIVMTPENRYKFYNLMKKYNIAIIEDGFNEELLYNSSHIFPICSLDNMNNGVVYIGSFSKILFPGMRIGWIFADKKVINKLESVKRCRNIHVSFLDQGILFDYLSNGGFEKYIKKIRKFYGDKFNFAYKCIKKYIKTEYILGDGGLHIFIKLKNIDTRVLLEKCYEKNVIFMPGDLFFTDNSGFDTLRLGFSRLSFEDIE NZ_CM000441.1 antiSMASHv7.0.0beta1-67b538a9 CDS 1434695 1435594 - gene_functions=biosynthetic-additional (rule-based-clusters) Dala_Dala_lig_N,biosynthetic-additional (rule-based-clusters) ATP-grasp_3,biosynthetic-additional (rule-based-clusters) RimK,biosynthetic-additional (rule-based-clusters) Dala_Dala_lig_C,biosynthetic-additional (rule-based-clusters) ATP-grasp;gene_kind=biosynthetic-additional;locus_tag=ctg1_1285;sec_met_domain=Dala_Dala_lig_N (E-value: 3.4e-23%2C bitscore: 79.9%2C seeds: 108%2C tool: rule-based-clusters),ATP-grasp_3 (E-value: 9.8e-12%2C bitscore: 43.0%2C seeds: 156%2C tool: rule-based-clusters),RimK (E-value: 1.8e-07%2C bitscore: 28.7%2C seeds: 173%2C tool: rule-based-clusters),Dala_Dala_lig_C (E-value: 4.4e-43%2C bitscore: 144.9%2C seeds: 204%2C tool: rule-based-clusters),ATP-grasp (E-value: 2.4e-05%2C bitscore: 21.7%2C seeds: 73%2C tool: rule-based-clusters);transl_table=11;translation=MKIAVIMGGISSEREVSLNSGKEIYNNLDKNKYEVVKVIIDDKKDIFTKIPEDIDFAILALHGKFGEDGCIQSILETMDIPYSGCGPLCSGMCMDKNITKKMLRDSNLPTAPWVLVKSVDEIDYDEIDNIGYPVFIKPNSGGSSVATFFIHSKDEVEEAVRKGLEVDEFVMIEKYIPGGEYTSFILNGEVFPTISIKSDSGFFDYEAKYSVEKGAKEEVVYLDEELQKRVNEISETCWKIFNCKAYVRVDMIISEGIPYVLELNTLPGMTQTSLIPRSAAARGIKYSELLDKLIEYSLN NZ_CM000441.1 antiSMASHv7.0.0beta1-67b538a9 CDS 1435852 1437108 + locus_tag=ctg1_1286;transl_table=11;translation=LKAEIISVGTEILLGDIVNTNSQFLAKELASLGIEVYHQSTVGDNKQRLLECFDESLKRSDFVITTGGLGPTGDDMTKETAAEYFGQKLELHKPSLEVLESFFVKTGKKMAENNMKQVYFPKDAIVLKNNNGTAPGAILKKDGKFIIVLPGPPREMKAMFNESVKPYLQQFTNEMLVSKTLRLYGIGESNLELEILDIINEQTNPTVALYAKELEVTIRITAKAENEREAFKLIKPVEEKIKSRVGKYVYTEGDISISEGETALEDAVSKLLVEKNLTIAVAESCTGGLVSSSLINYPGISSVFLEGCVTYSNDSKMKRLGVKRETLEEFGAVSEQTAIEMAEGVAKGLKANIGISTTGVAGPGGGTKEKPVGLVYTAIYINGKTIVKKNIFNGDRRKIRLRATRDLLNELRIQLEKL NZ_CM000441.1 antiSMASHv7.0.0beta1-67b538a9 CDS 1437178 1437957 + gene_functions=biosynthetic-additional (smcogs) SMCOG1179:hydrolase (Score: 171.1%3B E-value: 5.7e-52);gene_kind=biosynthetic-additional;locus_tag=ctg1_1287;transl_table=11;translation=MIKHIFCDLDGTLYENGTITKEDIVAIEEIEKKGVQFNVATGRIFKQAHNIIKDSLDMNGYYVCENGSFIYDKDYNVIFKRTIDDNLVKKVIDRFESSDAQLYFKYKGDVIVGSDTTAFRHYSSDFIVDPDFEKRSSFDNLIGNIGVCSENLEELSRIELYLKSEFSEVLEIYFSGTYTLNIVPKSVSKRGSIEHVIKTLNVSPDEVATIGDSPNDICMLEGFKYSFAMSKAREDVKQSANYVVDSVKSAIDVIMEINS NZ_CM000441.1 antiSMASHv7.0.0beta1-67b538a9 CDS 1438061 1438645 - locus_tag=ctg1_1288;transl_table=11;translation=MLMNTHFIMAKSILDNIDENKTFFISEKNFIYGNIKPDAFSKYKLKKHYLDESFNMIVSKINYLCSLNIDSLSKYFSVSRLSQELGVICHFLCDFFCVAHSERWEFKHSLNKHVTYERELGAFAKDVDLSKIKCGTINSSFEKFFTKLYSDYKKKTDYMNDLKFSAYTCNSVINYILDSILSNTIKSYHIANCG NZ_CM000441.1 antiSMASHv7.0.0beta1-67b538a9 CDS 1438845 1440275 - gene_functions=regulatory (smcogs) SMCOG1112:sigma-54 dependent trancsriptional regulator (Score: 378.9%3B E-value: 6e-115);gene_kind=regulatory;locus_tag=ctg1_1289;transl_table=11;translation=MNLDLEFYQKILEASHDEICVSDDKGIIIYCNKAFEENYGLKKEDILGKNVSFLEDSGYSTKSPIPIVLKTKTKFSLEQDTQTGKKLIITATPIFDENGNLEFTVENCRDITELNNIKNKLEDTKKQVKKYKSEVETLYRTALRIEDTVIMDGIVMRPIINTVNHVSKTDVSVLLLGESGTGKSSLARYIHHNSNRSNGPFITINCATISPQLLESELFGYTSGAFTGASTKGKVGLVELANGGTLFLDEIGDIPQNLQAKFLQLIQDRTFTPVGSLKNKKVDIRIISATNADLVSKVKEKKFREDLYYRLNVIEIKLPPLRERRDNLVEIIKYYFNRYSSDFNLNKTISKEAMDAIANYRFPGNIRELQNIIQKILLTCTDNHITIDDLPNILTKNIHITNNGNKTHISQINKVIISDSKSTNYKNKNFDTLIKEYEKNIILDAYEKFGSSYKVAKHLEISQSKANRLIRKYTNT NZ_CM000441.1 antiSMASHv7.0.0beta1-67b538a9 CDS 1440591 1441535 + gene_functions=transport (smcogs) SMCOG1166:transporter%2C EamA family (Score: 103.8%3B E-value: 1.9e-31);gene_kind=transport;locus_tag=ctg1_1290;transl_table=11;translation=MGEKSKGYVFIAIAGLLWATLGLFGKFLMGNGLTSEQVAFTRLFFGFIVLGVYSSIRTPQILKISKKGIIYSVIIGIICQAMFNLCYFKAIDIAGVSIAAVLLYTSPLFLAIFSKVCYKENITRSKLFSLILCFIGAIMAVTGGRLDFQGLNAFGLLLGVLSAIAYALMPTISKNALKEFSSSTILVYSFLFGAIFMIPSSRPWEILNYAKDLDVLSCMLMLGIVPAALAYIFYAAGISKGVELSVAGVVASVELVGSVIIGCTILGESFSLGKLFGVMLMLISAVVALNLSYDEIRIFYKSNKLKQIEKTESI NZ_CM000441.1 antiSMASHv7.0.0beta1-67b538a9 CDS 1441806 1442741 - gene_functions=biosynthetic-additional (rule-based-clusters) PF04055;gene_kind=biosynthetic-additional;locus_tag=ctg1_1291;sec_met_domain=PF04055 (E-value: 4.8e-16%2C bitscore: 57.3%2C seeds: 166%2C tool: rule-based-clusters);transl_table=11;translation=LDKFKYAFDDKRYHTWNYYLRNTFGEKVFKVSINAGFTCPNIDGSLGYGGCTYCSKEGSGDFAGNPKDNLISQFYNIKEMMLKKWPHAKYIGYFQAYTNTYAPLEVLKEKYETILELEDVIGLSISTRPDCLPDDVVEYLSELNKRTNLWVELGLQTIHDSTSKIINRGHDYKTFVEGVEKLKSKNIKVVVHIINGLPGEDYNMMMETAKAVGKMGVDGIKIHLLHVIKDTPMEKMLQNGMLTLMEQDEYINLVCDQLEILPETMIIHRLTGDGKRDELVGPIWSLKKWEILNQIDDTLKARNSYQGCKFV NZ_CM000441.1 antiSMASHv7.0.0beta1-67b538a9 CDS 1442861 1443409 - locus_tag=ctg1_1292;transl_table=11;translation=MYTNFNIDFNNFNKKENATKFMLMGVLLIILGLLCLTFKTLGIKLISWTFGIALLFFAYLNLKNINELKRYATKEEIKPSINIQWVLIIACILLFVFPQKIQSIFSLFLGFYLIFNQLVALVNSKNNPYSKFTTWNIVKILFGICLILSPLFLSRFIVSIMSFFIILFGLVLFFSGNTARKY NZ_CM000441.1 antiSMASHv7.0.0beta1-67b538a9 CDS 1443561 1443989 + locus_tag=ctg1_1293;transl_table=11;translation=MTKLWAIIFALLAGGSTALEAFINGELGKSTTALVATFISLTVGAIFFLASIIVTGDLKCLVSINGFNYKLLLGGVFGGLIIYFTVKAIPNLGVSNTLILTLVSQVLVGFFIDSVILGQETMHLYKYIGVILLILGTFFIVN NZ_CM000441.1 antiSMASHv7.0.0beta1-67b538a9 CDS 1444074 1444724 + locus_tag=ctg1_1294;transl_table=11;translation=LADEKFVMSFSGGKDSILALNRMLKKGYKPVALLTTISEEHGKSWTHNLEYNMLKQVSSNIGLPLLVAECGVEGYEESFERALIKAKNMGATICAYGDIDIESHRKWDTDRCEAVGMKVDLPLWQESREDLVYEFIDSGFCSVVTKVNLKHLGEEFLGKKLTRELVEKIKNAGADPCGEHGEYHTFVVDGPIFKKPVEYEVKGTLIKDGYGYLEIK NZ_CM000441.1 antiSMASHv7.0.0beta1-67b538a9 CDS 1444842 1446197 - gene_functions=transport (smcogs) SMCOG1086:MATE efflux family protein (Score: 368%3B E-value: 1e-111);gene_kind=transport;locus_tag=ctg1_1295;transl_table=11;translation=MDTKISINENMSLGKRFFKYLAPSVVAMWVFSLYTMVDGIFVSKGVGELALAAVNISMPFINFIFAVSLLFSTGASTIIAIYLGKKDIKSANEVFSFNLVSIIILSIIILAITFFNLDRLALFLGATESTIGMVKDYLGIIIFFNGFFIVSYSLEVIIKTDGFPILATVGVIISALTNIILDYLFVIEFGWGVKGAGIATVLSQVFSTIFFLIHFLRKNSTLNFSKFRIDFKTLRKIVFIGFPDSTTELSCGIVVLLFNLSLTKYIGENALIYYSVINYINTLVLMTMMGITQGMQPLTSFYYGAGNIDNVKKLLKMGIKATIIASVAVFAICMAFSGPIVSLFIHPEETMLFNEGVRVFKIFSISFLLVGINVIISGFFVSVEKPSISTVISLGRGLVIVVLSLISMILIFGGQGIWMTTIVSEFICLILSLVFLKKNFSTLDSNLNKVA NZ_CM000441.1 antiSMASHv7.0.0beta1-67b538a9 CDS 1446939 1447298 - locus_tag=ctg1_1296;transl_table=11;translation=MKLIDITPSILQSYINNIYNEHMLNSIKNQVDFIKSVLKESYRLKEISENICDFVTTPIKKNSSTSKFYTKQETQLLLEKSKNIPIGIPIFLILTLGLRFGEAVSLIWSDVDLDKKSHM