This BGC may be derived from merging overlapping BGC calls from multiple genome mining tools. The GFF attributes from the original BGC annotations are shown below in JSON format:

[
  {
    "SequenceID/Contig": "NC_013956",
    "start": "3654260",
    "end": "3667597",
    "annotation_tool": "antiSMASHv7.0.0beta1-67b538a9",
    "candidate_cluster_numbers": "8",
    "contig_edge": "False",
    "product": "phosphonate",
    "region_number": "8",
    "rules": "(phosphonates and minimum(1%2C [2-Hacid_dh_C%2C Aldedh%2C Aminotran_1_2%2C Aminotran_5%2C AurF%2C CTP_transf_like%2C DUF4992%2C Fe-ADH%2C HMGL-like%2C Metallophos_2%2C NTP_transf_3%2C NTP_transf_5%2C PALP%2C PEP_mutase%2C TPP_enzyme_C%2C TPP_enzyme_N%2C phosphonates]) and not (phosphonatesHydrolase or phosphonatesMeIsocitrateLyase))",
    "tool": "antismash"
  }
]

This phosphonate gene cluster produces 2-[hydroxy(phosphono)methyl]maleate (also known as pantaphos).

References:

• Polidore ALA, Furiassi L, Hergenrother PJ, Metcalf WW2021.A Phosphonate Natural Product Made by Pantoea ananatis is Necessary and Sufficient for the Hallmark Lesions of Onion Center Rot. mBio12:10.1128/mbio.03402-20. https://doi.org/10.1128/mbio.03402-20

• Polidore ALA, Caserio AD, Zhu L, Metcalf WW. Complete Biochemical Characterization of Pantaphos Biosynthesis Highlights an Unusual Role for a SAM-Dependent Methyltransferase. Angew Chem Int Ed Engl. 2024 Feb 12;63(7):e202317262. doi: 10.1002/anie.202317262.